Tassula Proikas-Cezanne

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Tassula Proikas-Cezanne

PI of Research Project 1:
“A role for human WIPI3 in lysosomal phosphoinositide signaling”

CONTACT

Prof. Dr. Tassula Proikas-Cezanne

Eberhard Karls Universität Tübingen
Interfakultäres Institut für Zellbiologie
Auf der Morgenstelle 15
D-72076 Tübingen
Germany

phone: +49 (0) 7071 29 78 895
fax: +49 (0) 7071 29 53 59
tassula.proikas-cezanne@uni-tuebingen.de
website Proikas-Cezanne Lab

 

 

 

 

KEY PUBLICATIONS

WIPI proteins: essential PtdIns3P effectors at the nascent autophagosome. Proikas-Cezanne T, Takacs Z, Dönnes P, Kohlbacher O (2015)  J Cell Sci 128:207-17

Neutral lipid stores and lipase PNPLA5 contribute to autophagosome biogenesis. Dupont N, Chauhan S, Arko-Mensah J, Castillo EF, Masedunskas A, Weigert R, Robenek H, Proikas-Cezanne T, Deretic V (2014) Curr Biol 24:609-20

Lipid droplet and early autophagosomal membrane targeting of Atg2A and Atg14L in human tumor cells. Pfisterer SG, Bakula D, Frickey T, Cezanne A, Brigger D, Tschan MP, Robenek H, Proikas-Cezanne T (2014)  J Lipid Res 55:1267-78

Modulation of glutamine metabolism by the PI3K-PKB-FOXO network regulates autophagy. Van der Vos KN, Eliasson P, Proikas-Cezanne T, Vervorrt S, Van Boxtel R, Putker M, Van Zutphen IJ, Mauthe M, Zellmer S, Pals C, Verhagen L, Braat K, Dansen TB, Holstege FCP, Gebhardt R, Burgering BMT, Coffer PJ (2012) Nat Cell Biol 14:829-37

Canonical and non-canonical autophagy: variations on a common theme of self-eating? Codogno P, Mehrpour M, Proikas-Cezanne T (2011)  Nat Rev Mol Cell Biol 13:7-12

Ca2+/Calmodulin-Dependent Kinase (CaMK) Signaling via CaMKI and AMP-Activated Protein Kinase Contributes to the Regulation of WIPI-1 at the Onset of Autophagy. Pfisterer SG, Mauthe M, Codogno P, Proikas-Cezanne T (2011)Mol Pharmacol 80:1066-75

Resveratrol-mediated autophagy requires WIPI-1 regulated LC3 lipidation in the absence of induced phagophore formation. Mauthe M, Jacob A, Freiberger S, Hentschel K, Stierhof YD, Codogno P, Proikas-Cezanne T (2011)  Autophagy 7:1448-61

AMPK-independent induction of autophagy by cytosolic Ca2+ increase. Grotemeier A, Alers S, Pfisterer SG, Paasch F, Daubrawa M, Dieterle A, Viollet B, Wesselborg S, Proikas-Cezanne T*, Stork B* (2010)  Cell Signal 22:914-25 (*equal senior author)

WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy. Proikas-Cezanne T, Waddell S, Gaugel A, Frickey T, Lupas A, Nordheim A (2004) Oncogene 23:9314-25

A “no-hybrids” screen for functional antagonizers of human p53 transactivator function: dominant negativity in fission yeast. Waddell S, Jenkins JR, Proikas-Cezanne T (2001) Oncogene 20:6001-8