2025
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(2023)[56] Lysosome-targeted multifunctional lipid probes reveal the sterol transporter NPC1 as a sphingosine interactor. Proc Natl Acad Sci U S A 120(11):e2213886120. Abstract
(2023)[55] ClC-7 drives intraphagosomal chloride accumulation to support hydrolase activity and phagosome resolution. J Cell Biol 222(6):e202208155. Abstract
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(2023)[51] Rab GTPase regulation of phagosome-lysosome fusion is bypassed in the presence of micromolar Ca2. (2023) J Cell Sci 136(9):jcs260806. Abstract
[50] CLCN7, a gene shared by autosomal recessive and autosomal dominant osteopetrosis. (2023) Bone 168:116639. Abstract
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2022
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[29] Pathogenic variants in GNPTAB and GNPTG encoding distinct subunits of GlcNAc-1-phosphotransferase differentially impact bone resorption in patients with mucolipidosis type II and III. (2021) Genet Med 23(12):2369-2377. Abstract
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2020
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2019
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[8] Lysosomal proteome analysis reveals that CLN3-defective cells have multiple enzyme deficiencies associated with changes in intracellular trafficking. Schmidtke C, Tiede S, Thelen M, Käkelä R, Jabs S, Makrypidi G, Sylvester M, Schweizer M, Braren I, Brocke-Ahmadinejad N, Cotman SL, Schulz A, Gieselmann V, Braulke T. (2019) J Biol Chem pii: jbc.RA119.008852. Abstract
[7] A mouse model for SPG48 reveals a block of autophagic flux upon disruption of adaptor protein complex five. Khundadze M, Ribaudo F, Hussain A, Rosentreter J, Nietzsche S, Thelen M, Winter D, Hoffmann B, Afzal MA, Hermann T, de Heus C, Piskor EM, Kosan C, Franzka P, von Kleist L, Stauber T, Klumperman J, Damme M, Proikas-Cezanne T, Hübner CA. (2019) Neurobiol Dis 127:419-431. Abstract
[6] ATG-18 and EPG-6 are Both Required for Autophagy but Differentially Contribute to Lifespan Control in Caenorhabditis elegans. Takacs Z, Sporbeck K, Stoeckle J, Prado Carvajal MJ, Grimmel M, Proikas-Cezanne T. (2019) Cells 8(3). pii: E236. Abstract
[5] Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes. Pasquier A, Vivot K, Erbs E, Spiegelhalter C, Zhang Z, Aubert V, Liu Z, Senkara M, Maillard E, Pinget M, Kerr-Conte J, Pattou F, Marciniak G, Ganzhorn A, Ronchi P, Schieber NL, Schwab Y, Saftig P, Goginashvili A, Ricci R. (2019) Nat Commun 10(1):3312. Abstract
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2018
[3] Lysosomal proteome and secretome analysis identifies missorted enzymes and their non-degraded substrates in mucolipidosis III mouse cells. Di Lorenzo G, Voltolini Velho R, Winter D, Thelen M, Ahmadi S, Schweizer M, De Pace R, Cornils K, Yorgan TA, Grüb S, Hermans-Borgmeyer I, Schinke T, Müller-Loennies S, Braulke T, Pohl S. (2018) Mol Cell Proteomics 17:1612-26. Abstract
[2] WIPI β-propellers function as scaffolds for STK11/LKB1-AMPK and AMPK-related kinase signaling in autophagy. Zuleger T, Heinzelbecker J, Takacs Z, Hunter C, Voelkl J, Lang F, Proikas-Cezanne T. (2018) Autophagy 14:1082-83 Abstract
[1] SGK1 Inhibits Autophagy in Murine Muscle Tissue. Zuleger T, Heinzelbecker J, Takacs Z, Hunter C, Voelkl J, Lang F, Proikas-Cezanne T. (2018) Oxid Med Cell Longev 2018:4043726. Abstract