Publications

2025

[74] Phosphoribosyl ubiquitination of SNARE proteins regulates autophagy during Legionella infection. Mukherjee R, Bhattacharya A, Tomaskovic I, Mello-Vieira J, Brunstein ME, Başoğlu M, Veenendaal T, Bailey H, Colby T, Misra M, Eimer S, Klumperman J, Münch C, Matic I, Dikic I. (2025) EMBO J doi: 10.1038/s44318-025-00483-4. Abstract

[73] VPS41 recruits biosynthetic LAMP-positive vesicles through interaction with Arl8b. Sanzà P, van der Beek J, Draper D, de Heus C, Veenendaal T, Brink CT, Farías GG, Liv N, Klumperman J. (2025) J Cell Biol 224(4):e202405002. Abstract

[72] Absolute Quantification of Lysosomal Proteins by Multiple Reaction Monitoring Mass Spectrometry and QconCAT Protein Standards. Mosen PR, Moharana B, Fajardo-Callejon S, Kaade E, Rösel N, Omidi M, Sakson R, Ruppert T, Pohl S, Gieselmann V, Winter D. (2025) bioRxiv https://doi.org/10.1101/2025.01.09.632238. Abstract

[71] Microglia and CD8+ T cell activation precede neuronal loss in a murine model of spastic paraplegia 15. Frolov A, Huang H, Schütz D, Köhne M, Blank-Stein N, Osei-Sarpong C, Büttner M, Elmzzahi T, Khundadze M, Zahid M, Reuter M, Becker M, De Domenico E, Bonaguro L, Kallies A, Morrison H, Hübner CA, Händler K, Stumm R, Mass E, Beyer MD. (2025) J Exp Med 222:e20232357. Abstract

2024

[70] GOLPH3 and GOLPH3L maintain Golgi localization of LYSET and a functional mannose 6-phosphate transport pathway. Brauer BK, Chen Z, Beirow F, Li J, Meisinger D, Capriotti E, Schweizer M, Wagner L, Wienberg J, Hobohm L, Blume L, Qiao W, Narimatsu Y, Carette JE, Clausen H, Winter D, Braulke T, Jabs S, Voss M. (2024) EMBO J doi: 10.1038/s44318-024-00305-z. Abstract

[69] Data-Independent Acquisition-Parallel Reaction Monitoring Acquisition Reveals Age-Dependent Alterations of the Lysosomal Proteome in a Mouse Model of Metachromatic Leukodystrophy. Sanner A, Hardt R, Matzner U, Winter D. (2024) Anal Chem 96(49):19567-19575. Abstract

[68] Delayed vacuolation in mammalian cells caused by hypotonicity and ion loss. Zook E, Pan YE, Wipplinger A, Kerschbaum HH, Clements RJ, Ritter M, Stauber T, Model MA. (2024) Sci Rep 14(1):29354. Abstract

[67] The lysosomal lipid transporter LIMP-2 is part of lysosome-ER STARD3-VAPB-dependent contact sites. Rudnik S, Heybrock S, Coyaud E, Xu Z, Neculai D, Raught B, Oorschot V, Heus C, Klumperman J, Saftig P. (2024) J Cell Sci 137(22):jcs261810. Abstract

[66] Mutations in CLCN6 as a Novel Genetic Cause of Neuronal Ceroid Lipofuscinosis. He H, Cao X, He F, Zhang W, Wang X, Peng P, Xie C, Yin F, Li D, Li J, Wang M, Klüssendorf M, Jentsch TJ, Stauber T, Peng J. (2024) Ann Neurol 96(3):608-24. Abstract

[65] Gain-of-function variants in CLCN7 cause hypopigmentation and lysosomal storage disease. Polovitskaya MM, Rana T, Ullrich K, Murko S, Bierhals T, Vogt G, Stauber T, Kubisch C, Santer R, Jentsch TJ. (2024) J Biol Chem 3:107437. Abstract

[64] Editorial: Intracellular ion channels in health and disease. Zifarelli G, Pusch M, Stauber T. (2024) Front Pharmacol 2:15:1430150. Abstract

[63] Lysosomal enzyme trafficking: from molecular mechanisms to human diseases. Braulke T, Carette JE, Palm W. (2024) Trends Cell Biol 34(3):198-210.  Abstract

[62] Neuroinflammatory disease signatures in SPG11-related hereditary spastic paraplegia patients. Krumm L, Pozner T, Zagha N, Coras R, Arnold P, Tsaktanis T, Scherpelz K, Davis MY, Kaindl J, Stolzer I, Süß P, Khundadze M, Hübner CA, Riemenschneider MJ, Baets J, Günther C, Jayadev S, Rothhammer V, Krach F, Winkler J, Winner B, Regensburger M. (2024) Acta Neuropathol 147(1): 28. Abstract

[61] Biallelic loss-of-function variants of ZFTRAF1 cause neurodevelopmental disorder with microcephaly and hypotonia. Asif M, Khayyat AIA, Alawbathani S, Abdullah U, Sanner A, Georgomanolis T, Haasters J, Becker K, Budde B, Becker C, Thiele H, Baig SM, Isidoro-García M, Winter D, Pogoda HM, Muhammad S, Hammerschmidt M, Kraft F, Kurth I, Martin HG, Wagner M, Nürnberg P, Hussain MS. (2024) Genet Med 26(7):101143. Abstract

[60] Loss of the HOPS complex disrupts early-to-late endosome transition, impairs endosomal recycling and induces accumulation of amphisomes. van der Beek J, de Heus C, Sanza P, Liv N, Klumperman J. (2024) Mol Biol Cell 35(3):ar40. Abstract

[59] Human WIPI β-propeller function in autophagy and neurodegeneration. Proikas-Cezanne T, Haas ML, Pastor-Maldonado CJ, Schüssele DS. (2024) FEBS Lett 598(1):127-139. Abstract

2023

[58] Proteomic investigation of neural stem cell to oligodendrocyte precursor cell differentiation reveals phosphorylation-dependent Dclk1 processing. Hardt R, Dehghani A, Schoor C, Gödderz M, Cengiz Winter N, Ahmadi S, Sharma R, Schork K, Eisenacher M, Gieselmann V, Winter D. (2023) Cell Mol Life Sci 80(9):260. Abstract

[57] Impaired Autophagic Clearance with a Gain-of-Function Variant of the Lysosomal Cl-/H+ Exchanger ClC-7. Bose S, de Heus C, Kennedy ME, Wang F, Jentsch TJ, Klumperman J, Stauber T. (2023) Biomolecules 13(12):1799. Abstract

[56] Lysosome-targeted multifunctional lipid probes reveal the sterol transporter NPC1 as a sphingosine interactor. Altuzar J, Notbohm J, Stein F, Haberkant P, Hempelmann P, Heybrock S, Worsch J, Saftig P, Höglinger D. (2023) Proc Natl Acad Sci U S A 120(11):e2213886120. Abstract

[55] ClC-7 drives intraphagosomal chloride accumulation to support hydrolase activity and phagosome resolution. Wu JZ, Zeziulia M, Kwon W, Jentsch TJ, Grinstein S, Freeman SA. (2023) J Cell Biol 222(6):e202208155. Abstract

[54] Consecutive functions of small GTPases guide HOPS-mediated tethering of late endosomes and lysosomes. Schleinitz A, Pöttgen LA, Keren-Kaplan T, Pu J, Saftig P, Bonifacino JS, Haas A, Jeschke A. (2023) Cell Rep 42(1):111969. Abstract

[53] The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extension. Sporbeck K, Haas ML, Pastor-Maldonado CJ, Schüssele DS, Hunter C, Takacs Z, Diogo de Oliveira AL, Franz-Wachtel M, Charsou C, Pfisterer SG, Gubas A, Haller PK, Knorr RL, Kaulich M, Macek B, Eskelinen EL, Simonsen A, Proikas-Cezanne T. (2023) Commun Biol 6(1):872. Abstract

[52] A lysosome membrane regeneration pathway depends on TBC1D15 and autophagic lysosomal reformation proteins. Bhattacharya A, Mukherjee R, Kuncha SK, Brunstein ME, Rathore R, Junek S, Münch C, Dikic I. (2023) Nat Cell Biol doi: 10.1038/s41556-023-01125-9. Abstract

[51] Rab GTPase regulation of phagosome-lysosome fusion is bypassed in the presence of micromolar Ca2. Becker J, Schleinitz A, Hermsen C, Rappold S, Saftig P, Jeschke A, Haas A. (2023) J Cell Sci 136(9):jcs260806. Abstract

[50] CLCN7, a gene shared by autosomal recessive and autosomal dominant osteopetrosis. Stauber T, Wartosch L, Vishnolia S, Schulz A, Kornak U. (2023) Bone 168:116639. Abstract

[49] Molecular basis of ClC-6 function and its impairment in human disease. Zhang B, Zhang S, Polovitskaya MM, Yi J, Ye B, Li R, Huang X, Yin J, Neuens S, Balfroid T, Soblet J, Vens D, Aeby A, Li X, Cai J, Song Y, Li Y, Tartaglia M, Li Y, Jentsch TJ, Yang M, Liu Z. (2023) Sci Adv 9(41):eadg4479. Abstract

[48] The mitochondrial Hsp70 controls the assembly of the F1FO-ATP synthase. Song J, Steidle L, Steymans I, Singh J, Sanner A, Böttinger L, Winter D, Becker T. (2023) Nat Commun 14(1):39. Abstract

[47] LAMTOR1 ubiquitination restricts its interaction with the vacuolar-type H+-ATPase, promotes autophagy and is controlled by USP32. Hertel A, Eimer S, Bremm A. (2023) Autophagy 1-2. doi: 10.1080/15548627.2023.2184958. Abstract

[46] Multi Cell Line Analysis of Lysosomal Proteomes Reveals Unique Features and Novel Lysosomal Proteins. Akter F, Bonini S, Ponnaiyan S, Kögler-Mohrbacher B, Bleibaum F, Damme M, Renard BY, Winter D. (2023) Mol Cell Proteomics 100509. doi: 10.1016/j.mcpro.2023.100509. Abstract

[45] Autophagy profiling in single cells with open source CellProfiler-based image analysis. Schüssele DS, Haller PK, Haas ML, Hunter C, Sporbeck K, Proikas-Cezanne T. (2023) Autophagy 19(1):338-351. Abstract

2022

[44] Inositol triphosphate-triggered calcium release from the endoplasmic reticulum triggers lysosome biogenesis via TFEB/ TFE3. Malek M, Wawrzyniak AM, Ebner M, Puchkov D, Haucke V. (2022) J Biol Chem 298: 101740. Abstract

[43] Inositol triphosphate signaling triggers lysosome biogenesis via calcium release from endoplasmic reticulum stores. Malek M, Haucke V. (2022)  Contact 5:251525642210970. Abstract

[42] USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction. Hertel A, Alves LM, Dutz H, Tascher G, Bonn F, Kaulich M, Dikic I, Eimer S, Steinberg F, Bremm A.(2022) Cell Rep 41(10):111653. Abstract

[41] The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection. Richards CM, Jabs S, Qiao W, Varanese LD, Schweizer M, Mosen PR, Riley NM, Klüssendorf M, Zengel JR, Flynn RA, Rustagi A, Widen JC, Peters CE, Ooi YS, Xie X, Shi PY, Bartenschlager R, Puscnik AS, Bogyo M, Bertozzi CR, Blish CA, Winter D, Nagamine CM, Braulke T, Carette JE. (2022) Science eabn5648.doi: 10.1126/science.abn5648. Abstract

[40] Proton-gated anion transport governs macropinosome shrinkage. Zeziulia M, Blin S, Schmitt FW, Lehmann M, Jentsch TJ. (2022) Nat Cell Biol 24(6):885-895. Abstract

[39] SPG15 protein deficits are at the crossroads between lysosomal abnormalities, altered lipid metabolism and synaptic dysfunction. Marrone L, Marchi PM, Webster CP, Marroccella R, Coldicott I, Reynolds S, Alves-Cruzeiro J, Yang ZL, Higginbottom A, Khundadze M, Shaw PJ, Hübner CA, Livesey MR, Azzouz M. (2022) Hum Mol Genet 21:ddac063. doi:10.1093/hmg/ddac063. Abstract

[38] P-Type Lectins. Dahms N, Braulke T, Varki A. (2022) In: Essentials of Glycobiology [Internet]. 4th edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory PressChapter 33.. Abstract

[37] IKCa channels control breast cancer metabolism including AMPK-driven autophagy. Gross D, Bischof H, Maier S, Sporbeck K, Birkenfeld AL, Malli R, Ruth P, Proikas-Cezanne T, Lukowski R. (2022) Cell Death Differ 13(10):902. Abstract

[36] Cross-linking of the endolysosomal system reveals potential flotillin structures and cargo. Singh J, Elhabashy H, Muthukottiappan P, Stepath M, Eisenacher M, Kohlbacher O, Gieselmann V, Winter D. (2022) Nat Commun 13(1):6212. Abstract

[35] S-palmitoylation determines TMEM55B-dependent positioning of lysosomes. Rudnik S, Heybrock S, Saftig P, Damme M. (2022) J Cell Sci 135:jcs258566. Abstract

[34] The ménage à trois of autophagy, lipid droplets and liver disease. Filali-Mouncef Y, Hunter C, Roccio F, Zagkou S, Dupont N, Primard C, Proikas-Cezanne T, Reggiori F. (2022) Autophagy 18:50-72. Review. Abstract

2021

[33] Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype. Soldati C, Lopez-Fabuel I, Wanderlingh LG, Garcia-Macia M, Monfregola J, Esposito A, Napolitano G, Guevara-Ferrer M, Scotto Rosato A, Krogsaeter EK, Paquet D, Grimm CM, Montefusco S, Braulke T, Storch S, Mole SE, De Matteis MA, Ballabio A, Sampaio JL, McKay T, Johannes L, Bolaños JP, Medina DL. (2021) EMBO Mol Med doi: 10.15252/emmm.202013742. Abstract

[32] Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage. Balboa E, Marín T, Oyarzún JE, Contreras PS, Hardt R, van den Bosch T, Alvarez AR, Rebolledo-Jaramillo B, Klein AD, Winter D, Zanlungo S. (2021) Cells 10:2159. Abstract

[31] RapiGest precipitation depends on peptide concentration. Mosen PR, Hardt R, Winter D. (2021) Proteomics 21(20):e2100129. Abstract

[30] Unique variants in CLCN3, encoding an endosomal anion/proton exchanger, underlie a spectrum of neurodevelopmental disorders. Duncan AR, Polovitskaya MM, Gaitán-Peñas H, Bertelli S, VanNoy GE, Grant PE, O’Donnell-Luria A, Valivullah Z, Lovgren AK, England EM, Agolini E, Madden JA, Schmitz-Abe K, Kritzer A, Hawley P, Novelli A, Alfieri P, Colafati GS, Wieczorek D, Platzer K, Luppe J, Koch-Hogrebe M, Abou Jamra R, Neira-Fresneda J, Lehman A, Boerkoel CF, Seath K, Clarke L; CAUSES Study; van Ierland Y, Argilli E, Sherr EH, Maiorana A, Diel T, Hempel M, Bierhals T, Estévez R, Jentsch TJ, Pusch M, Agrawal PB. (2021) Am J Hum Genet 108(8):1450-1465. Abstract

[29] Pathogenic variants in GNPTAB and GNPTG encoding distinct subunits of GlcNAc-1-phosphotransferase differentially impact bone resorption in patients with mucolipidosis type II and III. Di Lorenzo G, Westermann LM, Yorgan TA, Stürznickel J, Ludwig NF, Ammer LS, Baranowsky A, Ahmadi S, Pourbarkhordariesfandabadi E, Breyer SR, Board TN, Foster A, Mercer J, Tylee K, Velho RV, Schweizer M, Renné T, Braulke T, Randon DN, Sperb-Ludwig F, de Camargo Pinto LL, Moreno CA, Cavalcanti DP, Amling M, Kutsche K, Winter D, Muschol NM, Schwartz IVD, Rolvien T, Danyukova T, Schinke T, Pohl S. (2021) Genet Med 23(12):2369-2377. Abstract

[28] The lysosomal membrane-export of metabolites and beyond. Rudnik S, Damme D. (2021) FEBS J 288:4168-82. Review. Abstract

[27] Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1-dependent TFEB/TFE3 regulation. van der Welle REN, Jobling R, Burns C, Sanza P, van der Beek JA, Fasano A, Chen L, Zwartkruis FJ, Zwakenberg S, Griffin EF, Ten Brink C, Veenendaal T, Liv N, van Ravenswaaij-Arts CMA, Lemmink HH, Pfundt R, Blaser S, Sepulveda C, Lozano AM, Yoon G, Santiago-Sim T, Asensio CS, Caldwell GA, Caldwell KA, Chitayat D, Klumperman J. (2021) EMBO Mol Med e13258.doi: 10.15252/emmm.202013258. Abstract

[26] How Lysosomes Sense, Integrate, and Cope with Stress. Saftig P, Puertollano R. (2021) Trends Biochem Sci 46(2):97-112. Review. Abstract

[25] Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation. Khundadze M, Ribaudo F, Hussain A, Stahlberg H, Brocke-Ahmadinejad N, Franzka P, Varga RE, Zarkovic M, Pungsrinont T, Kokal M, Ganley IG, Beetz C, Sylvester M, Hübner CA. (2021) Autophagy doi: 10.1080/15548627.2021.1891848. Abstract

[24] A proteomic view on lysosomes. Muthukottiappan P, Winter D. (2021) Mol Omics 17(6):842-859. Review. Abstract

[23] Pancreatic β-Cell-Specific Deletion of VPS41 Causes Diabetes Due to Defects in Insulin Secretion. Burns CH, Yau B, Rodriguez A, Triplett J, Maslar D, An YS, van der Welle REN, Kossina RG, Fisher MR, Strout GW, Bayguinov PO, Veenendaal T, Chitayat D, Fitzpatrick JAJ, Klumperman J, Kebede MA, Asensio CS. (2021) Diabetes 70(2):436-448. Abstract

[22] Neurodegeneration Upon Dysfunction of Endosomal/Lysosomal CLC Chloride Transporters. Bose S, He H, Stauber T. (2021) Front Cell Dev Biol 9:639231. doi: 10.3389/fcell.2021.639231. Abstract

[21] West Syndrome Caused By a Chloride/Proton Exchange-Uncoupling CLCN6 Mutation Related to Autophagic-Lysosomal Dysfunction. He H, Cao X, Yin F, Wu T, Stauber T, Peng J. (2021) Mol Neurobiol doi: 10.1007/s12035-021-02291-3. Abstract

[20] ER – lysosome contacts at a pre-axonal region regulate axonal lysosome availability. Özkan N, Koppers M, van Soest I, van Harten A, Jurriens D, Liv N, Klumperman J, Kapitein LC, Hoogenraad CC, Farías GG. (2021) Nat Commun 12(1):4493. Abstract

[19] Targeted Quantification of the Lysosomal Proteome in Complex Samples. Mosen P, Sanner A, Singh J, Winter D. (2021) Proteomes 9(1):4. Abstract

2020

[18] Cholesterol Handling in Lysosomes and Beyond. Meng Y, Heybrock S, Neculai D, Saftig P. (2020) Trends Cell Biol 30(6):452-466. Abstract

[17] A Recurrent Gain-of-Function Mutation in CLCN6, Encoding the ClC-6 Cl−/H+-Exchanger, Causes Early-Onset Neurodegeneration. Polovitskaya MM, Barbini C, Martinelli D, Harms FL, Cole FS, Calligari P, Bocchinfuso G, Stella L, Ciolfi A, Niceta M, Rizza T, Shinawi M, Sisco K, Johannsen J, Denecke J, Carrozzo R, Wegner DJ, Kutsche K, Tartaglia M, Jentsch TJ. (2020) Am J Hum Genet 107(6):1062-1077. Abstract

[16] Comprehensive Draft of the Mouse Embryonic Fibroblast Lysosomal Proteome by Mass Spectrometry Based Proteomics. Ponnaiyan S, Akter F, Singh J, Winter D. (2020) Sci Data 7(1):68. Abstract

[15] Uncoupling Endosomal CLC chloride/proton Exchange Causes Severe Neurodegeneration. Weinert S, Gimber N, Deuschel D, Stuhlmann T, Puchkov D, Farsi Z, Ludwig CF, Novarino G, López-Cayuqueo KI, Planells-Cases R, Jentsch TJ. (2020) EMBO J 39(9):e103358. Abstract

[14] Drp1 modulates mitochondrial stress responses to mitotic arrest.. Peña-Blanco A, Haschka MD, Jenner A, Zuleger T, Proikas-Cezanne T, Villunger A, García-Sáez AJ. (2020) Cell Death Differ 27(9):2620-2634. Abstract

[13] The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons. Lüningschrör P, Werner G, Stroobants S, Kakuta S, Dombert B, Sinske D, Wanner R, Lüllmann-Rauch R, Wefers B, Wurst W, D’Hooge R, Uchiyama Y, Sendtner M, Haass C, Saftig P, Knöll B, Capell A, Damme M. (2020) Cell Rep 30:3506-3519.e6. Abstract

[12] Systematic Comparison of Strategies for the Enrichment of Lysosomes by Data Independent Acquisition. Singh J, Kaade E, Muntel J, Bruderer R, Reiter L, Thelen M, Winter D. (2020) J Proteome Res 19(1):371-81. Abstract

2019

[11] Lysosomal Integral Membrane protein-2 (LIMP-2/SCARB2) Is Involved in Lysosomal Cholesterol Export. Heybrock S, Kanerva K, Meng Y, Ing C, Liang A, Xiong ZJ, Weng X, Ah Kim Y, Collins R, Trimble W, Pomès R, Privé GG, Annaert W, Schwake M, Heeren J, Lüllmann-Rauch R, Grinstein S, Ikonen E, Saftig P, Neculai D. (2019) Nat Commun 10(1):3521 Abstract

[10] ER-phagy and human diseases. (Review) Hübner CA, Dikic I. (2019) Cell Death Differ doi: 10.1038/s41418-019-0444-0. Abstract

[9] A Mathematical Model of Lysosomal Ion Homeostasis Points to Differential Effects of Cl− Transport in Ca2+ Dynamics. Astaburuaga R, Quintanar Haro OD, Stauber T, Relógio A. (2019) Cells 8(10). pii: E1263. Abstract (*These authors contributed equally to the work)

[8] Lysosomal proteome analysis reveals that CLN3-defective cells have multiple enzyme deficiencies associated with changes in intracellular trafficking. Schmidtke C, Tiede S, Thelen M, Käkelä R, Jabs S, Makrypidi G, Sylvester M, Schweizer M, Braren I, Brocke-Ahmadinejad N, Cotman SL, Schulz A, Gieselmann V, Braulke T. (2019) J Biol Chem pii: jbc.RA119.008852. Abstract

[7] A mouse model for SPG48 reveals a block of autophagic flux upon disruption of adaptor protein complex five. Khundadze M, Ribaudo F, Hussain A, Rosentreter J, Nietzsche S, Thelen M, Winter D, Hoffmann B, Afzal MA, Hermann T, de Heus C, Piskor EM, Kosan C, Franzka P, von Kleist L, Stauber T, Klumperman J, Damme M, Proikas-Cezanne T, Hübner CA. (2019) Neurobiol Dis 127:419-431. Abstract

[6] ATG-18 and EPG-6 are Both Required for Autophagy but Differentially Contribute to Lifespan Control in Caenorhabditis elegans. Takacs Z, Sporbeck K, Stoeckle J, Prado Carvajal MJ, Grimmel M, Proikas-Cezanne T. (2019) Cells 8(3). pii: E236. Abstract

[5] Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes. Pasquier A, Vivot K, Erbs E, Spiegelhalter C, Zhang Z, Aubert V, Liu Z, Senkara M, Maillard E, Pinget M, Kerr-Conte J, Pattou F, Marciniak G, Ganzhorn A, Ronchi P, Schieber NL, Schwab Y, Saftig P, Goginashvili A, Ricci R. (2019) Nat Commun 10(1):3312. Abstract

[4] Automated Detection of Autophagy Response Using Single Cell-Based Microscopy Assays. Mueller AJ, Proikas-Cezanne T. (2019) Methods Mol Biol 1880:429-445. Abstract

2018

[3] Lysosomal proteome and secretome analysis identifies missorted enzymes and their non-degraded substrates in mucolipidosis III mouse cells.  Di Lorenzo G, Voltolini Velho R, Winter D, Thelen M, Ahmadi S, Schweizer M, De Pace R, Cornils K, Yorgan TA, Grüb S, Hermans-Borgmeyer I, Schinke T, Müller-Loennies S, Braulke T, Pohl S. (2018) Mol Cell Proteomics 17:1612-26. Abstract 

[2] WIPI β-propellers function as scaffolds for STK11/LKB1-AMPK and AMPK-related kinase signaling in autophagy. Zuleger T, Heinzelbecker J, Takacs Z, Hunter C, Voelkl J, Lang F, Proikas-Cezanne T. (2018) Autophagy 14:1082-83 Abstract 

[1] SGK1 Inhibits Autophagy in Murine Muscle Tissue. Zuleger T, Heinzelbecker J, Takacs Z, Hunter C, Voelkl J, Lang F, Proikas-Cezanne T. (2018) Oxid Med Cell Longev 2018:4043726. Abstract